The fanatical and twisted attitudes of evolution’s defenders enticed Lewis to agree that “evolution is the central and radical lie in the whole web of falsehood that now governs our lives”. We’ve been blinded to asking certain questions. Darwinism helps restrict what questions we ask of nature.Just consider that at the end of his life Darwin regretted his statements about "evolution", grieving that people had constructed what he called their own "religion" from them.
Lewis was troubled by the growing intolerance he saw among evolutionists who seemed to treat any criticism of their views as an attack upon science itself. Lewis had a sharply different vision of what science should be like.
In his view there was nothing anti-science about questioning dogmatic claims made in the name of science. Indeed, he thought good science recognized the benefits of questions and criticisms in helping science correct its own errors. Lewis’s growing awareness of the fallibility of science was expressed powerfully in his final book, The Discarded Image…
Lewis argues in the book that scientific theories are supposals rather than facts. These supposals try to account for as many facts as possible, with as few assumptions as possible, but according to Lewis such supposals by scientists are provisional - they can be wrong. Lewis further argued that scientific revolutions often are not the result simply of discovering new facts; that science often presents a view popular at a given time and based upon assumptions already in place.
“The Darwinian revolution in biology was certainly not brought about by the discovery of new facts.” - CSLewis