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...I thought of Willis myself....I had a bizarre idea while reading the book, because I kept picturing Bruce Willis as Hodges (even though they are physically different)... so I imagined that Mr. Mercedes could work as a plot for Die Hard 6. McClane would be retired, the threat would be just the killer and etc, I think it could work.
She does have the right 'crazyskinny' vibe though Another choice would be Lili Taylor.Great choices. Amanda Plummer is a bit too old I think.
Tom Welling as Brady is problematic for me though. He hasn't proved himself outside of Smallville. Would rather see Aaron Paul.
Love your choices for Janey and Jerome.
Several possibilities for Hodges. Crowe is good. Cranston would be awesome - and a nifty Breaking Bad reunion if Aaron Paul was cast.
Bruce Willis would be good too.